Collegium to Present Xtampza ER(TM) Oral Human Abuse Potential Data at the College on Problems of Drug Dependence 77th Annual Meeting
The poster, titled "Oral Human Abuse Potential of Oxycodone DETERx®: An Abuse-deterrent, Extended-release Formulation in Recreational Opioid Users", summarizes data from a human abuse potential (HAP) study designed to evaluate the abuse potential and pharmacokinetics of oral administration of intact Xtampza ER™ (oxycodone extended-release), oral administration of chewed Xtampza ER, and oral administration of crushed immediate-release (IR) oxycodone in non-dependent, recreational drug abusers.
The oral HAP study demonstrated that chewed Xtampza ER had significantly lower peak "Drug Liking" (Emax) when compared with crushed IR oxycodone (p < 0.0001). Furthermore, there was no difference in the pharmacokinetics when Xtampza ER was chewed or taken intact as determined by bioequivalence measures (Cmax and AUC).
Title: Oral Human Abuse Potential of Oxycodone DETERx: An Abuse-deterrent, Extended-release Formulation in Recreational Opioid Users
Date and Time:
Location: Arizona Biltmore,
Collegium is a specialty pharmaceutical company focused on developing a portfolio of products that incorporate its patent-protected DETERx technology platform for the treatment of chronic pain and other diseases. The DETERx oral drug delivery technology is designed to provide extended-release delivery, unique abuse-deterrent properties, and flexible dose administration options. The new drug application, or NDA, filing for Xtampza ER, the Company's lead product candidate, was accepted by the
This press release contains forward-looking statements within the meaning of The Private Securities Litigation Reform Act of 1995. We may, in some cases, use terms such as "predicts," "believes," "potential," "proposed," "continue," "estimates," "anticipates," "expects," "plans," "intends," "may," "could," "might," "will," "should" or other words that convey uncertainty of future events or outcomes to identify these forward-looking statements. Such statements are subject to numerous important factors, risks and uncertainties that may cause actual events or results to differ materially from the company's current expectations. For example, there can be no guarantee that we will obtain approval for Xtampza or any of our other product candidates from the
Douglas CarlsonVice President, Corporate Development firstname.lastname@example.org